WPs » WP5 » Deliverables WP5

Deliverables WP5

5.1

Optimised protocol for metabonomic analysis

18

5.2

Generation of metabolic profiling of data from autopsied CNS tissue (2 batches, n=75 each)

18

5.3

Generation of metabolic profiling of data from cellular and mouse Models FUS & TARDBP, also UNC and DCTN mice: Discovery (n=24 cellular, n=90 mice)

18

5.4

Generation of metabolic profiling data from iPS cells discovery (n=25) and replication cohorts (n=25)

30

5.5

Generation of metabolic profiling of data from cellular and mouse Models FUS & TARDBP, also UNC and DCTN mice: Replication (n=24 cellular, n=90 mice)

30

5.6

Generation of metabonomic data from discovery and replication set of plasma samples from prospective cohorts

36

5.7

Multivariate models of metabolic profiling data from both discovery and replication cohorts for association with ALS

48